Antiretroviral Therapy Dose Adjustments Based On Calculated Creatinine Clearance
نویسندگان
چکیده
منابع مشابه
Effects of moderate-dose versus high-dose trimethoprim on serum creatinine and creatinine clearance and adverse reactions.
The effects of a 10-day course of moderate-dose (10 mg/kg/day) or high-dose (20 mg/kg/day) trimethoprim therapy on serum creatinine, measured creatinine clearance, urinary creatinine excretion, and serum folate were studied in 20 healthy volunteers. Serum creatinine concentrations increased significantly during trimethoprim therapy, began to decrease near day 10, and returned to baseline during...
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Glomerular filtration rate (GFR) is commonly assessed by measurement of endogenous creatinine clearance (Ccr). Several formulae have been described to calculate Ccr from plasma creatinine. I have evaluated the effectiveness of four formulae in 35 healthy subjects (21M and 14F, 18-34 years) and in 41 patients (24M, 17F, 20-69 years) attending a renal clinic with diminished renal function (serum ...
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In today’s medicine, drug therapy represents an important tool to treat or control disease. Dosing drugs is based on the assumption that a particular dose will yield a predefined concentration in the circulation and thereby establish the desired therapeutic effect. The fact that liver and kidney function may affect this relationship is appreciated, as is the fact that the use of co-medication p...
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ژورنال
عنوان ژورنال: East African Medical Journal
سال: 2009
ISSN: 0012-835X
DOI: 10.4314/eamj.v86i4.46950